BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM74453
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50>79400±0 nM
Citation PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM74453
n/a
NameBDBM74453
Synonyms:4-(7-methoxy-4-phenyl-2-quinolinyl)morpholine;oxalic acid | 4-(7-methoxy-4-phenyl-2-quinolyl)morpholine;oxalic acid | 4-(7-methoxy-4-phenylquinolin-2-yl)morpholine;oxalic acid | MLS000048790 | SMR000061969 | cid_2998399 | ethanedioic acid;4-(7-methoxy-4-phenyl-quinolin-2-yl)morpholine
TypeSmall organic molecule
Emp. Form.C20H20N2O2
Mol. Mass.320.385
SMILESCOc1ccc2c(cc(nc2c1)N1CCOCC1)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: