| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Ligand | BDBM74479 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 |
|---|
| IC50 | >79400±0 nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 40530.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35236 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
|
|
|
|---|
| BDBM74479 |
|---|
| n/a |
|---|
| Name | BDBM74479 |
|---|
| Synonyms: | 2-(2-Chloro-acetylamino)-2-[4-(1-ethoxycarbonyl-2,2,2-trifluoro-1-hydroxy-ethyl)-phenylamino]-3,3,3-trifluoro-propionic acid ethyl ester | 2-[4-[[1-carbethoxy-1-[(2-chloroacetyl)amino]-2,2,2-trifluoro-ethyl]amino]phenyl]-3,3,3-trifluoro-2-hydroxy-propionic acid ethyl ester | 2-[4-[[2-[(2-chloro-1-oxoethyl)amino]-3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-yl]amino]phenyl]-3,3,3-trifluoro-2-hydroxypropanoic acid ethyl ester | MLS000589015 | SMR000212628 | cid_3351058 | ethyl 2-[4-[[2-(2-chloranylethanoylamino)-3-ethoxy-1,1,1-tris(fluoranyl)-3-oxidanylidene-propan-2-yl]amino]phenyl]-3,3,3-tris(fluoranyl)-2-oxidanyl-propanoate | ethyl 2-[4-[[2-[(2-chloroacetyl)amino]-3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-yl]amino]phenyl]-3,3,3-trifluoro-2-hydroxypropanoate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H19ClF6N2O6 |
|---|
| Mol. Mass. | 508.797 |
|---|
| SMILES | CCOC(=O)C(O)(c1ccc(NC(NC(=O)CCl)(C(=O)OCC)C(F)(F)F)cc1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
