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TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM74503
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50>79400±0 nM
Citation PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM74503
n/a
NameBDBM74503
Synonyms:4-[(4-bromo-1-ethyl-pyrazole-3-carbonyl)thiocarbamoylamino]benzoic acid methyl ester | 4-[[[[(4-bromo-1-ethyl-3-pyrazolyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acid methyl ester | MLS000700620 | SMR000227880 | cid_994540 | methyl 4-[(4-bromanyl-1-ethyl-pyrazol-3-yl)carbonylcarbamothioylamino]benzoate | methyl 4-[(4-bromo-1-ethylpyrazole-3-carbonyl)carbamothioylamino]benzoate | methyl 4-[({[(4-bromo-1-ethyl-1H-pyrazol-3-yl)carbonyl]amino}carbothioyl)amino]benzoate
TypeSmall organic molecule
Emp. Form.C15H15BrN4O3S
Mol. Mass.411.274
SMILESCCn1cc(Br)c(n1)C(=O)NC(=S)Nc1ccc(cc1)C(=O)OC
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: