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TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM74521
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50>79400±0 nM
Citation PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM74521
n/a
NameBDBM74521
Synonyms:1-[4-[3-[4-(4-nitrophenyl)piperazino]propoxy]benzyl]isonipecotic acid methyl ester | 1-[[4-[3-[4-(4-nitrophenyl)-1-piperazinyl]propoxy]phenyl]methyl]-4-piperidinecarboxylic acid methyl ester | MLS000763507 | SMR000336850 | cid_2766344 | methyl 1-(4-{3-[4-(4-nitrophenyl)piperazino]propoxy}benzyl)-4-piperidinecarboxylate | methyl 1-[[4-[3-[4-(4-nitrophenyl)piperazin-1-yl]propoxy]phenyl]methyl]piperidine-4-carboxylate
TypeSmall organic molecule
Emp. Form.C27H36N4O5
Mol. Mass.496.5985
SMILESCOC(=O)C1CCN(Cc2ccc(OCCCN3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)cc2)CC1
Structure
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