Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM74538 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 |
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IC50 | 10923±371 nM |
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Citation | PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM74538 |
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n/a |
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Name | BDBM74538 |
Synonyms: | 3-[[1,3-diketo-2-(4-nitrophenyl)isoindoline-5-carbonyl]amino]-4-methyl-benzoic acid | 4-methyl-3-({[2-(4-nitrophenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid | 4-methyl-3-[[2-(4-nitrophenyl)-1,3-bis(oxidanylidene)isoindol-5-yl]carbonylamino]benzoic acid | 4-methyl-3-[[2-(4-nitrophenyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acid | 4-methyl-3-[[[2-(4-nitrophenyl)-1,3-dioxo-5-isoindolyl]-oxomethyl]amino]benzoic acid | MLS001194401 | SMR000555144 | cid_2867365 |
Type | Small organic molecule |
Emp. Form. | C23H15N3O7 |
Mol. Mass. | 445.3811 |
SMILES | Cc1ccc(cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(cc1)[N+]([O-])=O)C(O)=O |
Structure |
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