Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM46240 |
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Substrate/Competitor | n/a |
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Meas. Tech. | SAR analysis of compounds that inhibit HePTP - Set 2 |
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IC50 | 1360±n/a nM |
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Citation | PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM46240 |
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n/a |
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Name | BDBM46240 |
Synonyms: | 4-[(E)-2-[3-bromanyl-4-[(4-fluorophenyl)methoxy]phenyl]-1-cyano-ethenyl]benzoic acid | 4-[(E)-2-[3-bromo-4-(4-fluorobenzyl)oxy-phenyl]-1-cyano-vinyl]benzoic acid | 4-[(E)-2-[3-bromo-4-[(4-fluorophenyl)methoxy]phenyl]-1-cyanoethenyl]benzoic acid | MLS-0412109.0001 | cid_2240797 |
Type | Small organic molecule |
Emp. Form. | C23H15BrFNO3 |
Mol. Mass. | 452.273 |
SMILES | OC(=O)c1ccc(cc1)C(=C/c1ccc(OCc2ccc(F)cc2)c(Br)c1)\C#N |
Structure |
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