| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group I member 2 |
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| Ligand | BDBM75446 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) |
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| EC50 | >116193±n/a nM |
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| Citation |  PubChem, PC Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear receptor subfamily 1 group I member 2 |
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| Name: | Nuclear receptor subfamily 1 group I member 2 |
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| Synonyms: | NR1I2 | NR1I2_HUMAN | Orphan nuclear receptor PAR1 | Orphan nuclear receptor PXR | PXR | Pregnane X receptor | SXR | Steroid and xenobiotic receptor | nuclear receptor subfamily 1 group I member 2 isoform 1 |
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| Type: | Nuclear receptor |
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| Mol. Mass.: | 49774.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O75469 |
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| Residue: | 434 |
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| Sequence: | MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE
RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSS
GCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLL
PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR
VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF
ATPLMQELFGITGS
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| BDBM75446 |
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| n/a |
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| Name | BDBM75446 |
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| Synonyms: | 2-Methoxy-N-(5-thiophen-2-yl-[1,3,4]thiadiazol-2-yl)-acetamide | 2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide | 2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)ethanamide | 2-methoxy-N-[5-(2-thienyl)-1,3,4-thiadiazol-2-yl]acetamide | MLS000034756 | SMR000005332 | cid_649189 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9N3O2S2 |
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| Mol. Mass. | 255.317 |
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| SMILES | COCC(=O)Nc1nnc(s1)-c1cccs1 |
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| Structure | 
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