| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75724 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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|
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| BDBM75724 |
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| n/a |
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| Name | BDBM75724 |
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| Synonyms: | 1-(1-adamantylcarbonyl)-3,5-dimethyl-1H-pyrazole | 1-adamantyl-(3,5-dimethyl-1-pyrazolyl)methanone | 1-adamantyl-(3,5-dimethylpyrazol-1-yl)methanone | MLS000063040 | SMR000071865 | cid_2932043 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22N2O |
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| Mol. Mass. | 258.3587 |
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| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)C(=O)n1nc(C)cc1C |TLB:5:3:11:6.9.8,THB:2:3:9:1.11.8,5:6:11:3.12.2| |
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| Structure | 
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