| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75667 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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|
|
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| BDBM75667 |
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| n/a |
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| Name | BDBM75667 |
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| Synonyms: | 2-(7-fluoranyl-4-oxidanylidene-pyrrolo[1,2-a]quinoxalin-5-yl)-N-[2-(4-methylpiperazin-1-yl)ethyl]ethanamide | 2-(7-fluoro-4-keto-pyrrolo[1,2-a]quinoxalin-5-yl)-N-[2-(4-methylpiperazino)ethyl]acetamide | 2-(7-fluoro-4-oxo-5-pyrrolo[1,2-a]quinoxalinyl)-N-[2-(4-methyl-1-piperazinyl)ethyl]acetamide | 2-(7-fluoro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)-N-[2-(4-methylpiperazin-1-yl)ethyl]acetamide | MLS001117041 | SMR000627119 | cid_22522721 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24FN5O2 |
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| Mol. Mass. | 385.4353 |
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| SMILES | CN1CCN(CCNC(=O)Cn2c3cc(F)ccc3n3cccc3c2=O)CC1 |
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| Structure | 
|
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