Reaction Details |
| Report a problem with these data |
Target | Type-1 angiotensin II receptor |
---|
Ligand | BDBM38993 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor |
---|
IC50 | 3673±288 nM |
---|
Citation | PubChem, PC Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor PubChem Bioassay(2010)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Type-1 angiotensin II receptor |
---|
Name: | Type-1 angiotensin II receptor |
Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
Type: | Protein |
Mol. Mass.: | 41080.75 |
Organism: | Homo sapiens (Human) |
Description: | P30556 |
Residue: | 359 |
Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
|
|
|
BDBM38993 |
---|
n/a |
---|
Name | BDBM38993 |
Synonyms: | (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene | MLS000085704 | SMR000020833 | cid_5286934 |
Type | Small organic molecule |
Emp. Form. | C12H22O4S2 |
Mol. Mass. | 294.431 |
SMILES | CCCCS(=O)(=O)\C=C/C=C\S(=O)(=O)CCCC |
Structure |
|