| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM67244 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor |
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| IC50 | 2909±218 nM |
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| Citation |  PubChem, PC Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM67244 |
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| n/a |
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| Name | BDBM67244 |
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| Synonyms: | 6-ethyl-2-(2-pyridinyl)-3H-thieno[2,3-d]pyrimidin-4-one | 6-ethyl-2-(2-pyridinyl)thieno[2,3-d]pyrimidin-4(3H)-one | 6-ethyl-2-(2-pyridyl)-3H-thieno[2,3-d]pyrimidin-4-one | 6-ethyl-2-pyridin-2-yl-3H-thieno[2,3-d]pyrimidin-4-one | MLS000705563 | SMR000232055 | cid_852940 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11N3OS |
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| Mol. Mass. | 257.311 |
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| SMILES | CCc1cc2c(nc([nH]c2=O)-c2ccccn2)s1 |
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| Structure | 
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