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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Type-1 angiotensin II receptor | ||
| Ligand | BDBM43484 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor | ||
| IC50 | 18639±2779 nM | ||
| Citation |  PubChem, PC Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor PubChem Bioassay(2010)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Type-1 angiotensin II receptor | |||
| Name: | Type-1 angiotensin II receptor | ||
| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 41080.75 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P30556 | ||
| Residue: | 359 | ||
| Sequence: |
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| BDBM43484 | |||
| n/a | |||
| Name | BDBM43484 | ||
| Synonyms: | (3aR,5R,5aR,8aR,9S,9aS)-5,8a-dimethyl-1-methylidene-9-oxidanyl-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-quinone | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | Helenalin | MLS000728512 | SMR000445626 | cid_23205 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H18O4 | ||
| Mol. Mass. | 262.301 | ||
| SMILES | C[C@@H]1C[C@H]2OC(=O)C(=C)[C@H]2[C@H](O)[C@@]2(C)[C@H]1C=CC2=O |c:17| | ||
| Structure | 
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