Reaction Details |
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Target | Neuropeptides B/W receptor type 1 |
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Ligand | BDBM75896 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) |
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IC50 | 575±n/a nM |
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Citation | PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Neuropeptides B/W receptor type 1 |
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Name: | Neuropeptides B/W receptor type 1 |
Synonyms: | GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36111.82 |
Organism: | Homo sapiens (Human) |
Description: | gi_119607128 |
Residue: | 328 |
Sequence: | MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA
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BDBM75896 |
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n/a |
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Name | BDBM75896 |
Synonyms: | 5-chloranyl-2-(4-ethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one | 5-chloro-2-(4-ethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone | 5-chloro-2-(4-ethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one | SR-02000000367 | SR-02000000367-1 | cid_46172935 |
Type | Small organic molecule |
Emp. Form. | C19H17ClN2O3 |
Mol. Mass. | 356.803 |
SMILES | CCc1ccc(cc1)-n1ncc(Cl)c(Oc2ccc(OC)cc2)c1=O |
Structure |
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