| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM55196 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
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| IC50 | 2520±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM55196 |
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| n/a |
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| Name | BDBM55196 |
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| Synonyms: | 2-(2,4-Dimethyl-5-oxo-4,5-dihydro-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-6-yl)-N-phenethyl-acetamide | 2-(2,4-dimethyl-5-oxidanylidene-thieno[3,4]pyrrolo[1,3-d]pyridazin-6-yl)-N-(2-phenylethyl)ethanamide | 2-(2,4-dimethyl-5-oxo-6-thieno[3,4]pyrrolo[1,3-d]pyridazinyl)-N-(2-phenylethyl)acetamide | 2-(2,4-dimethyl-5-oxothieno[3,4]pyrrolo[1,3-d]pyridazin-6-yl)-N-(2-phenylethyl)acetamide | 2-(5-keto-2,4-dimethyl-thieno[3,4]pyrrolo[1,3-d]pyridazin-6-yl)-N-phenethyl-acetamide | MLS000076138 | SMR000000722 | cid_650226 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O2S |
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| Mol. Mass. | 380.463 |
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| SMILES | Cc1cc2n(C)c3c(cnn(CC(=O)NCCc4ccccc4)c3=O)c2s1 |
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| Structure | 
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