| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM75986 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
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| IC50 | 4062±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM75986 |
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| n/a |
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| Name | BDBM75986 |
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| Synonyms: | 3,4,6-trimethyl-N-(4-sulfamoylbenzyl)coumarilamide | 3,4,6-trimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide | 3,4,6-trimethyl-N-[(4-sulfamoylphenyl)methyl]-2-benzofurancarboxamide | MLS000705412 | N-[4-(aminosulfonyl)benzyl]-3,4,6-trimethyl-1-benzofuran-2-carboxamide | SMR000232046 | cid_986536 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O4S |
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| Mol. Mass. | 372.438 |
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| SMILES | Cc1c(oc2cc(C)cc(C)c12)C(=O)NCc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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