Ki Summary

Reaction Details

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Target

Photoreceptor-specific nuclear receptor

Ligand

BDBM31069

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists

IC50

3496±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Photoreceptor-specific nuclear receptor

Name:

Photoreceptor-specific nuclear receptor

Synonyms:

NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor

Type:

PROTEIN

Mol. Mass.:

44699.83

Organism:

Homo sapiens (Human)

Description:

ChEMBL_401901

Residue:

410

Sequence:

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

BDBM31069

n/a

Name

BDBM31069

Synonyms:

5-bromanyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]furan-2-carboxamide | 5-bromo-N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)-2-furamide | 5-bromo-N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-2-furamide | 5-bromo-N-[4-(2-oxazolo[4,5-b]pyridinyl)phenyl]-2-furancarboxamide | 5-bromo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]furan-2-carboxamide | MLS000061716 | SMR000070185 | cid_1161055

Type

Small organic molecule

Emp. Form.

C17H10BrN3O3

Mol. Mass.

384.184

SMILES

Brc1ccc(o1)C(=O)Nc1ccc(cc1)-c1nc2ncccc2o1

Structure