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TargetPhotoreceptor-specific nuclear receptor
LigandBDBM76009
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
IC50 1457±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Photoreceptor-specific nuclear receptor
Name:Photoreceptor-specific nuclear receptor
Synonyms:NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:PROTEIN
Mol. Mass.:44699.83
Organism:Homo sapiens (Human)
Description:ChEMBL_401901
Residue:410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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  Blast E-value cutoff:
BDBM76009
n/a
NameBDBM76009
Synonyms:3-(3,4-dimethoxyphenyl)-N-[2-[(4-fluorobenzyl)amino]-2-keto-ethyl]-4-keto-phthalazine-1-carboxamide | 3-(3,4-dimethoxyphenyl)-N-[2-[(4-fluorophenyl)methylamino]-2-oxidanylidene-ethyl]-4-oxidanylidene-phthalazine-1-carboxamide | 3-(3,4-dimethoxyphenyl)-N-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-4-oxo-1-phthalazinecarboxamide | 3-(3,4-dimethoxyphenyl)-N-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-4-oxophthalazine-1-carboxamide | MLS000936274 | SMR000620955 | cid_22334119
TypeSmall organic molecule
Emp. Form.C26H23FN4O5
Mol. Mass.490.483
SMILESCOc1ccc(cc1OC)-n1nc(C(=O)NCC(=O)NCc2ccc(F)cc2)c2ccccc2c1=O
Structure
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