| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM76015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
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| IC50 | 2280±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM76015 |
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| n/a |
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| Name | BDBM76015 |
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| Synonyms: | 3-Methoxy-naphthalene-2-carboxylic acid (2-oxo-2H-chromen-6-yl)-amide | 3-methoxy-N-(2-oxidanylidenechromen-6-yl)naphthalene-2-carboxamide | 3-methoxy-N-(2-oxo-1-benzopyran-6-yl)-2-naphthalenecarboxamide | 3-methoxy-N-(2-oxochromen-6-yl)naphthalene-2-carboxamide | MLS001219448 | N-(2-ketochromen-6-yl)-3-methoxy-2-naphthamide | SMR000612701 | cid_965782 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15NO4 |
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| Mol. Mass. | 345.3481 |
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| SMILES | COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(=O)ccc2c1 |
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| Structure | 
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