| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptides B/W receptor type 1 |
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| Ligand | BDBM75901 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7): Intracellular calcium release |
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| IC50 | 281±n/a nM |
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| Citation |  PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7): Intracellular calcium release PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neuropeptides B/W receptor type 1 |
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| Name: | Neuropeptides B/W receptor type 1 |
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| Synonyms: | GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36111.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_119607128 |
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| Residue: | 328 |
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| Sequence: | MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA
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| BDBM75901 |
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| n/a |
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| Name | BDBM75901 |
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| Synonyms: | 5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one | 5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone | 5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one | ML181 | SR-02000000372 | SR-02000000372-1 | cid_46172919 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17ClN2O3 |
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| Mol. Mass. | 356.803 |
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| SMILES | COc1ccc(Oc2c(Cl)cnn(-c3cc(C)cc(C)c3)c2=O)cc1 |
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| Structure | 
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