Ki Summary

Reaction Details

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Target

Intestinal-type alkaline phosphatase 1

Ligand

BDBM40697

Substrate/Competitor

n/a

Meas. Tech.

Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay

EC50

21000±n/a nM

Citation

PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Intestinal-type alkaline phosphatase 1

Name:

Intestinal-type alkaline phosphatase 1

Synonyms:

Alpi | PPBI1_RAT

Type:

Enzyme Catalytic Domain

Mol. Mass.:

58396.39

Organism:

Rattus norvegicus (Rat)

Description:

P15693

Residue:

540

Sequence:

MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS

BDBM40697

n/a

Name

BDBM40697

Synonyms:

4-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-6-yl)-1,2-benzenediol | 4-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-6-yl)benzene-1,2-diol | 4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)benzene-1,2-diol | 4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)pyrocatechol | MLS000530540 | SMR000135520 | cid_877570

Type

Small organic molecule

Emp. Form.

C11H10N2O2S

Mol. Mass.

234.274

SMILES

Oc1ccc(cc1O)-c1cn2CCSc2n1

Structure