| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM57870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay |
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| EC50 | 35500±n/a nM |
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| Citation |  PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM57870 |
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| n/a |
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| Name | BDBM57870 |
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| Synonyms: | (2Z)-1-ethyl-2-[(1-ethyl-6-methyl-2-quinolin-1-iumyl)methylidene]thieno[3,2-e][1,3]benzothiazole;iodide | (2Z)-1-ethyl-2-[(1-ethyl-6-methyl-quinolin-1-ium-2-yl)methylene]thieno[3,2-e][1,3]benzothiazole;iodide | (2Z)-1-ethyl-2-[(1-ethyl-6-methyl-quinolin-1-ium-2-yl)methylidene]thieno[3,2-e][1,3]benzothiazole;iodide | (2Z)-1-ethyl-2-[(1-ethyl-6-methylquinolin-1-ium-2-yl)methylidene]thieno[3,2-e][1,3]benzothiazole;iodide | 1-ethyl-2-[(Z)-(1-ethylthieno[3,2-e][1,3]benzothiazol-2(1H)-ylidene)methyl]-6-methylquinolinium | MLS000724336 | SMR000305930 | cid_16193285 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N2S2 |
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| Mol. Mass. | 403.582 |
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| SMILES | CCN1\C(Sc2ccc3sccc3c12)=C\c1ccc2cc(C)ccc2[n+]1CC |
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| Structure | 
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