| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
|---|
| Ligand | BDBM46229 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay |
|---|
| EC50 | 5570±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Intestinal-type alkaline phosphatase 1 |
|---|
| Name: | Intestinal-type alkaline phosphatase 1 |
|---|
| Synonyms: | Alpi | PPBI1_RAT |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 58396.39 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P15693 |
|---|
| Residue: | 540 |
|---|
| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
|
|
|
|---|
| BDBM46229 |
|---|
| n/a |
|---|
| Name | BDBM46229 |
|---|
| Synonyms: | 4-chloranyl-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoyl-benzamide | 4-chloro-3-sulfamoyl-N-thiochroman-4-yl-benzamide | 4-chloro-N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-sulfamoylbenzamide | 4-chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoylbenzamide | MLS-0336143.0001 | cid_16330874 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15ClN2O3S2 |
|---|
| Mol. Mass. | 382.885 |
|---|
| SMILES | NS(=O)(=O)c1cc(ccc1Cl)C(=O)NC1CCSc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
