| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM39735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | 7930±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM39735 |
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| n/a |
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| Name | BDBM39735 |
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| Synonyms: | MLS000566764 | N-(diphenylmethyl)-2-[methyl-[(4-oxidanylidene-1H-quinazolin-2-yl)methyl]amino]ethanamide | N-(diphenylmethyl)-2-[methyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamide | N-benzhydryl-2-[(4-keto-1H-quinazolin-2-yl)methyl-methyl-amino]acetamide | N-benzhydryl-2-[methyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamide | SMR000153739 | cid_2439531 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24N4O2 |
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| Mol. Mass. | 412.4837 |
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| SMILES | CN(CC(=O)NC(c1ccccc1)c1ccccc1)Cc1nc2ccccc2c(=O)[nH]1 |
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| Structure | 
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