BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetIntestinal-type alkaline phosphatase 1
LigandBDBM57462
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay
IC50 6960±n/a nM
Citation PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Intestinal-type alkaline phosphatase 1
Name:Intestinal-type alkaline phosphatase 1
Synonyms:Alpi | PPBI1_RAT
Type:Enzyme Catalytic Domain
Mol. Mass.:58396.39
Organism:Rattus norvegicus (Rat)
Description:P15693
Residue:540
Sequence:
MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM57462
n/a
NameBDBM57462
Synonyms:1-(3-chlorophenyl)-3-(3,3-diphenylpropyl)thiourea | MLS000573451 | N-(3-chlorophenyl)-N'-(3,3-diphenylpropyl)thiourea | SMR000194953 | cid_1336020
TypeSmall organic molecule
Emp. Form.C22H21ClN2S
Mol. Mass.380.934
SMILESClc1cccc(NC(=S)NCCC(c2ccccc2)c2ccccc2)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: