| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
|---|
| Ligand | BDBM76193 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay |
|---|
| IC50 | 3680±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Intestinal-type alkaline phosphatase 1 |
|---|
| Name: | Intestinal-type alkaline phosphatase 1 |
|---|
| Synonyms: | Alpi | PPBI1_RAT |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 58396.39 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P15693 |
|---|
| Residue: | 540 |
|---|
| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
|
|
|
|---|
| BDBM76193 |
|---|
| n/a |
|---|
| Name | BDBM76193 |
|---|
| Synonyms: | (2Z)-2-[2-[2-(3-methoxy-3-oxidanylidene-propylidene)hydrazinyl]-4-oxidanylidene-1,3-thiazol-5-ylidene]ethanoic acid | (2Z)-2-[2-[2-(3-methoxy-3-oxopropylidene)hydrazinyl]-4-oxo-1,3-thiazol-5-ylidene]acetic acid | (2Z)-2-[2-[2-(3-methoxy-3-oxopropylidene)hydrazinyl]-4-oxo-5-thiazolylidene]acetic acid | (2Z)-2-[4-keto-2-[N'-(3-keto-3-methoxy-propylidene)hydrazino]-2-thiazolin-5-ylidene]acetic acid | 3-({5-[1-Carboxy-meth-(Z)-ylidene]-4-oxo-4,5-dihydro-thiazol-2-yl}-hydrazono)-propionic acid methyl ester | MLS000777481 | SMR000413875 | cid_16682271 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H9N3O5S |
|---|
| Mol. Mass. | 271.25 |
|---|
| SMILES | COC(=O)CC=NNC1=NC(=O)C(S1)=CC(O)=O |w:6.6,14.15,t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
