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TargetIntestinal-type alkaline phosphatase 1
LigandBDBM76251
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay
IC50 2600±n/a nM
Citation PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Intestinal-type alkaline phosphatase 1
Name:Intestinal-type alkaline phosphatase 1
Synonyms:Alpi | PPBI1_RAT
Type:Enzyme Catalytic Domain
Mol. Mass.:58396.39
Organism:Rattus norvegicus (Rat)
Description:P15693
Residue:540
Sequence:
MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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  Blast E-value cutoff:
BDBM76251
n/a
NameBDBM76251
Synonyms:1-(4-phenylbutyl)-3-[[(2S,5S)-5-[(4-phenylphenyl)methyl]-2-oxolanyl]methyl]urea | 1-(4-phenylbutyl)-3-[[(2S,5S)-5-[(4-phenylphenyl)methyl]oxolan-2-yl]methyl]urea | 1-[[(2S,5S)-5-(4-phenylbenzyl)tetrahydrofuran-2-yl]methyl]-3-(4-phenylbutyl)urea | MLS002603698 | SMR001522428 | cid_42627831
TypeSmall organic molecule
Emp. Form.C29H34N2O2
Mol. Mass.442.5925
SMILESO=C(NCCCCc1ccccc1)NC[C@@H]1CC[C@@H](Cc2ccc(cc2)-c2ccccc2)O1
Structure
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