Ki Summary

Reaction Details

Report a problem with these data

Target

Intestinal-type alkaline phosphatase

Ligand

BDBM67333

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay - Set 2

IC50

34000±n/a nM

Citation

PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay - Set 2 PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Intestinal-type alkaline phosphatase

Name:

Intestinal-type alkaline phosphatase

Synonyms:

ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN

Type:

PROTEIN

Mol. Mass.:

56804.94

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1278525

Residue:

528

Sequence:

MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP

BDBM67333

n/a

Name

BDBM67333

Synonyms:

8-(dimethylamino)-10-(2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4-dione | 8-(dimethylamino)-10-(2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4-quinone | 8-(dimethylamino)-10-[2,3,4,5-tetrakis(oxidanyl)pentyl]benzo[g]pteridine-2,4-dione | 8-Dimethylamino-10-(2,3,4,5-tetrahydroxy-pentyl)-10H-benzo[g]pteridine-2,4-dione | MLS001213081 | SMR000517413 | cid_3138587

Type

Small organic molecule

Emp. Form.

C17H21N5O6

Mol. Mass.

391.3785

SMILES

CN(C)c1ccc2nc3c(nc(=O)[nH]c3=O)n(CC(O)C(O)C(O)CO)c2c1

Structure