| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM75383 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 3 |
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| EC50 | >64000±n/a nM |
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| Citation |  PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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|
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| BDBM75383 |
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| n/a |
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| Name | BDBM75383 |
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| Synonyms: | 2-[5-[(2,6-difluorobenzyl)thio]-4-(2-furfuryl)-1,2,4-triazol-3-yl]pyridine | 2-[5-[(2,6-difluorophenyl)methylsulfanyl]-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]pyridine | 2-[5-[(2,6-difluorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridine | 2-[5-[[2,6-bis(fluoranyl)phenyl]methylsulfanyl]-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]pyridine | KSC-5-287A11 | KUC104186N | cid_16447354 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H14F2N4OS |
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| Mol. Mass. | 384.402 |
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| SMILES | Fc1cccc(F)c1CSc1nnc(-c2ccccn2)n1Cc1ccco1 |
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| Structure | 
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