| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM55601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay |
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| IC50 | 730±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
|
|
|
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| BDBM55601 |
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| n/a |
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| Name | BDBM55601 |
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| Synonyms: | 1-(2,3-dihydroindol-1-yl)-2-[[(5E)-4-(4-ethoxyphenyl)-5-(3-indolylidene)-1H-1,2,4-triazol-3-yl]thio]ethanone | 1-(2,3-dihydroindol-1-yl)-2-[[(5E)-4-(4-ethoxyphenyl)-5-indol-3-ylidene-1H-1,2,4-triazol-3-yl]sulfanyl]ethanone | 1-indolin-1-yl-2-[[(5E)-5-indol-3-ylidene-4-p-phenetyl-1H-1,2,4-triazol-3-yl]thio]ethanone | MLS000724638 | SMR000237500 | cid_6161440 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H25N5O2S |
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| Mol. Mass. | 495.595 |
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| SMILES | CCOc1ccc(cc1)-n1c(SCC(=O)N2CCc3ccccc23)nnc1-c1c[nH]c2ccccc12 |
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| Structure | 
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