| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-1 |
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| Ligand | BDBM61402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of NALP1 in yeast using a Caspase-1-ASC counter screen. |
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| IC50 | 15900±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of NALP1 in yeast using a Caspase-1-ASC counter screen. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Caspase-1 |
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| Name: | Caspase-1 |
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| Synonyms: | CASP1 | CASP1_HUMAN | Caspase | Caspase 1 | ICE | IL1BC | IL1BCE | Interleukin-1 beta convertase | Interleukin-1 beta-converting enzyme |
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| Type: | Enzyme |
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| Mol. Mass.: | 45154.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29466 |
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| Residue: | 404 |
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| Sequence: | MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS
VIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN
PAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRT
GAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIR
EGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVG
VSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEY
ACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
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| BDBM61402 |
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| n/a |
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| Name | BDBM61402 |
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| Synonyms: | (Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)piperidine | (Z)-but-2-enedioic acid;2-(2,2-dicyclohexylethyl)piperidine | 2-(2,2-dicyclohexylethyl)piperidine;maleic acid | 2-[2,2-DICYCLOHEXYLETHYL]PIPERIDINE MALEATE SALT | CHEMBL75880 | MLS000028601 | Perhexiline | SMR000058713 | cid_5284439 | perhexiline maleate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H35N |
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| Mol. Mass. | 277.4879 |
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| SMILES | C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1 |
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| Structure | 
|
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