| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM76113 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor |
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| EC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM76113 |
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| n/a |
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| Name | BDBM76113 |
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| Synonyms: | 3-({[1-(1-Benzyl-1H-tetrazol-5-yl)-2-methyl-propyl]-furan-2-ylmethyl-amino}-methyl)-6-methoxy-1H-quinolin-2-one | 3-[[2-furanylmethyl-[2-methyl-1-[1-(phenylmethyl)-5-tetrazolyl]propyl]amino]methyl]-6-methoxy-1H-quinolin-2-one | 3-[[[1-(1-benzyltetrazol-5-yl)-2-methyl-propyl]-(2-furfuryl)amino]methyl]-6-methoxy-carbostyril | 3-[[[1-(1-benzyltetrazol-5-yl)-2-methylpropyl]-(furan-2-ylmethyl)amino]methyl]-6-methoxy-1H-quinolin-2-one | 3-[[furan-2-ylmethyl-[2-methyl-1-[1-(phenylmethyl)-1,2,3,4-tetrazol-5-yl]propyl]amino]methyl]-6-methoxy-1H-quinolin-2-one | MLS000122860 | SMR000123514 | cid_3203085 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30N6O3 |
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| Mol. Mass. | 498.5762 |
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| SMILES | COc1ccc2[nH]c(=O)c(CN(Cc3ccco3)C(C(C)C)c3nnnn3Cc3ccccc3)cc2c1 |
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| Structure | 
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