| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
|---|
| Ligand | BDBM50061921 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor |
|---|
| EC50 | >100000±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Type-1 angiotensin II receptor |
|---|
| Name: | Type-1 angiotensin II receptor |
|---|
| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 41080.75 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P30556 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
|
|
|
|---|
| BDBM50061921 |
|---|
| n/a |
|---|
| Name | BDBM50061921 |
|---|
| Synonyms: | 4-Methyl-N-(4-phenyl-thiazol-2-yl)-benzenesulfonamide | CHEMBL136883 | cid_748055 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O2S2 |
|---|
| Mol. Mass. | 330.425 |
|---|
| SMILES | Cc1ccc(cc1)S(=O)(=O)Nc1nc(cs1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
