| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM66136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase |
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| IC50 | 20300±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM66136 |
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| n/a |
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| Name | BDBM66136 |
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| Synonyms: | 2-amino-5-(3-hydroxy-6-keto-xanthen-9-yl)benzoic acid | 2-amino-5-(3-hydroxy-6-oxo-9-xanthenyl)benzoic acid | 2-amino-5-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid | 2-azanyl-5-(3-oxidanyl-6-oxidanylidene-xanthen-9-yl)benzoic acid | MLS001216583 | SMR000544115 | cid_3801816 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13NO5 |
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| Mol. Mass. | 347.3209 |
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| SMILES | Nc1ccc(cc1C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |
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| Structure | 
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