Ki Summary

Reaction Details

Report a problem with these data

Target

Intestinal-type alkaline phosphatase

Ligand

BDBM57432

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase

IC50

42400±n/a nM

Citation

PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Intestinal-type alkaline phosphatase

Name:

Intestinal-type alkaline phosphatase

Synonyms:

ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN

Type:

PROTEIN

Mol. Mass.:

56804.94

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1278525

Residue:

528

Sequence:

MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP

BDBM57432

n/a

Name

BDBM57432

Synonyms:

1-(3-chloranyl-2-methyl-phenyl)-3-(3,3-diphenylpropyl)thiourea | 1-(3-chloro-2-methyl-phenyl)-3-(3,3-diphenylpropyl)thiourea | 1-(3-chloro-2-methylphenyl)-3-(3,3-diphenylpropyl)thiourea | MLS000575407 | N-(3-chloro-2-methylphenyl)-N'-(3,3-diphenylpropyl)thiourea | SMR000196641 | cid_2171132

Type

Small organic molecule

Emp. Form.

C23H23ClN2S

Mol. Mass.

394.96

SMILES

Cc1c(Cl)cccc1NC(=S)NCCC(c1ccccc1)c1ccccc1

Structure