| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM60675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase |
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| IC50 | 19800±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM60675 |
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| n/a |
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| Name | BDBM60675 |
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| Synonyms: | (5E)-2-amino-5-(2-furanylmethylidene)-4-thiazolone | (5E)-2-amino-5-(2-furfurylidene)-2-thiazolin-4-one | (5E)-2-amino-5-(furan-2-ylmethylidene)-1,3-thiazol-4-one | (5E)-2-azanyl-5-(furan-2-ylmethylidene)-1,3-thiazol-4-one | MLS000709076 | SMR000282943 | cid_1243441 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H6N2O2S |
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| Mol. Mass. | 194.21 |
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| SMILES | NC1=NC(=O)C(S1)=Cc1ccco1 |w:7.8,t:1| |
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| Structure | 
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