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TargetCaspase-3
LigandBDBM76650
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay
IC50 31300±n/a nM
Citation PubChem, PC Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Caspase-3
Name:Caspase-3
Synonyms:Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein
Type:Hydrolase; heterotetramer of two heterodimers
Mol. Mass.:31607.55
Organism:Homo sapiens (Human)
Description:n/a
Residue:277
Sequence:
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
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  Blast E-value cutoff:
BDBM76650
n/a
NameBDBM76650
Synonyms:2-bromobenzoic acid [1-(4-methylphenyl)ethylideneamino] ester | 2-bromobenzoic acid [1-(p-tolyl)ethylideneamino] ester | MLS001209490 | SMR000513341 | The compound has not trivial name. | [1-(4-methylphenyl)ethylideneamino] 2-bromanylbenzoate | [1-(4-methylphenyl)ethylideneamino] 2-bromobenzoate | cid_708195
TypeSmall organic molecule
Emp. Form.C16H14BrNO2
Mol. Mass.332.192
SMILESCC(=NOC(=O)c1ccccc1Br)c1ccc(C)cc1
Structure
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