| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-3 |
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| Ligand | BDBM76722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay |
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| IC50 | 7100±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Caspase-3 |
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| Name: | Caspase-3 |
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| Synonyms: | Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein |
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| Type: | Hydrolase; heterotetramer of two heterodimers |
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| Mol. Mass.: | 31607.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 277 |
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| Sequence: | MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
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|
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| BDBM76722 |
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| n/a |
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| Name | BDBM76722 |
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| Synonyms: | 2-(3H-benzimidazole-5-carbonylamino)-4-methyl-thiazole-5-carboxylic acid ethyl ester | 2-[[3H-benzimidazol-5-yl(oxo)methyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester | MLS001173978 | SMR000595705 | cid_9110686 | ethyl 2-(3H-benzimidazol-5-ylcarbonylamino)-4-methyl-1,3-thiazole-5-carboxylate | ethyl 2-(3H-benzimidazole-5-carbonylamino)-4-methyl-1,3-thiazole-5-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O3S |
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| Mol. Mass. | 330.362 |
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| SMILES | CCOC(=O)c1sc(NC(=O)c2ccc3nc[nH]c3c2)nc1C |
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| Structure | 
|
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