Reaction Details |
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Target | Sentrin-specific protease 8 |
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Ligand | BDBM61205 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay |
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IC50 | 2640±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sentrin-specific protease 8 |
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Name: | Sentrin-specific protease 8 |
Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24104.52 |
Organism: | Homo sapiens (Human) |
Description: | gi_262118306 |
Residue: | 212 |
Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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BDBM61205 |
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n/a |
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Name | BDBM61205 |
Synonyms: | 1,8-bis(azanyl)-6-methoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile;ethanoic acid | 1,8-diamino-6-methoxy-3-pyrrolidino-2,7-naphthyridine-4-carbonitrile | MLS001007001 | SMR000349800 | acetic acid;1,8-diamino-6-methoxy-3-(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile | acetic acid;1,8-diamino-6-methoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | acetic acid;1,8-diamino-6-methoxy-3-pyrrolidino-2,7-naphthyridine-4-carbonitrile | cid_16196095 |
Type | Small organic molecule |
Emp. Form. | C14H16N6O |
Mol. Mass. | 284.3164 |
SMILES | COc1cc2c(C#N)c(nc(N)c2c(N)n1)N1CCCC1 |
Structure |
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