| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Ligand | BDBM76205 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. |
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| IC50 | 5440±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alkaline phosphatase, tissue-nonspecific isozyme |
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| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57306.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448917 |
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| Residue: | 524 |
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| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
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| BDBM76205 |
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| n/a |
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| Name | BDBM76205 |
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| Synonyms: | 4-Fluoro-N-[4-hydroxy-3-(1H-[1,2,4]triazol-3-ylsulfanyl)-phenyl]-2-methyl-benzenesulfonamide | 4-fluoranyl-2-methyl-N-[4-oxidanyl-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]benzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]-2-methylbenzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2-methyl-benzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2-methylbenzenesulfonamide | MLS001217329 | SMR000612865 | cid_1094879 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13FN4O3S2 |
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| Mol. Mass. | 380.417 |
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| SMILES | Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(O)c(Sc2nnc[nH]2)c1 |
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| Structure | 
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