| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 6 |
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| Ligand | BDBM76622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay |
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| IC50 | 11100±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 6 |
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| Name: | Sentrin-specific protease 6 |
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| Synonyms: | KIAA0797 | SENP6 | SENP6_HUMAN | SSP1 | SUMO-1-specific protease | SUSP1 | Sentrin-specific protease 6 (SENP6) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 126147.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9GZR1 |
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| Residue: | 1112 |
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| Sequence: | MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE
DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN
TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRL
QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ
AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ
TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC
SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR
RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD
PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT
NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE
ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP
PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ
RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK
YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN
PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS
STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ
WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK
VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE
DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD
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| BDBM76622 |
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| n/a |
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| Name | BDBM76622 |
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| Synonyms: | (4-benzoxyphenyl)-pyrrolidino-methanethione | (4-phenylmethoxyphenyl)-(1-pyrrolidinyl)methanethione | (4-phenylmethoxyphenyl)-pyrrolidin-1-yl-methanethione | (4-phenylmethoxyphenyl)-pyrrolidin-1-ylmethanethione | 1-{[4-(benzyloxy)phenyl]carbonothioyl}pyrrolidine | MLS001163371 | SMR000497289 | cid_800556 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NOS |
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| Mol. Mass. | 297.415 |
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| SMILES | S=C(N1CCCC1)c1ccc(OCc2ccccc2)cc1 |
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| Structure | 
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