| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-7 |
|---|
| Ligand | BDBM77506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 |
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| EC50 | 20198±n/a nM |
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| Citation |  PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
|---|
| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
|---|
| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
|
|
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| BDBM77506 |
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| n/a |
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| Name | BDBM77506 |
|---|
| Synonyms: | 2-keto-6-nitro-N-[1-(tetrahydrofuryl)ethyl]chromene-3-carboxamide | 6-nitro-2-oxidanylidene-N-[1-(oxolan-2-yl)ethyl]chromene-3-carboxamide | 6-nitro-2-oxo-N-[1-(2-oxolanyl)ethyl]-1-benzopyran-3-carboxamide | 6-nitro-2-oxo-N-[1-(oxolan-2-yl)ethyl]chromene-3-carboxamide | 6-nitro-2-oxo-N-[1-(tetrahydro-2-furanyl)ethyl]-2H-chromene-3-carboxamide | MLS000684331 | SMR000295896 | cid_2970929 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O6 |
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| Mol. Mass. | 332.308 |
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| SMILES | CC(NC(=O)c1cc2cc(ccc2oc1=O)[N+]([O-])=O)C1CCCO1 |
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| Structure | 
|
|---|
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