| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-7 |
|---|
| Ligand | BDBM77507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 |
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| EC50 | >85301±n/a nM |
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| Citation |  PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
|---|
| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
|---|
| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
|
|
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| BDBM77507 |
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| n/a |
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| Name | BDBM77507 |
|---|
| Synonyms: | 2-(4-methyl-phenyl)-3-hydroxy-4(1H)-quinolinone-7-carboxylic acid N-propylamide | 2-(4-methylphenyl)-3-oxidanyl-4-oxidanylidene-N-propyl-1H-quinoline-7-carboxamide | 3-hydroxy-2-(4-methylphenyl)-4-oxo-N-propyl-1H-quinoline-7-carboxamide | 3-hydroxy-4-keto-N-propyl-2-(p-tolyl)-1H-quinoline-7-carboxamide | MLS000888975 | SMR000453628 | cid_16745864 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C20H20N2O3 |
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| Mol. Mass. | 336.3844 |
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| SMILES | CCCNC(=O)c1ccc2c(O)c(O)c(nc2c1)-c1ccc(C)cc1 |
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| Structure | 
|
|---|
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