BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMitochondrial import inner membrane translocase subunit TIM10
LigandBDBM67793
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50 20700±n/a nM
Citation PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Mitochondrial import inner membrane translocase subunit TIM10
Name:Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:Enzyme Catalytic Domain
Mol. Mass.:10303.50
Organism:Saccharomyces cerevisiae S288c
Description:gi_285809906
Residue:93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM67793
n/a
NameBDBM67793
Synonyms:2-(7,8-Dimethyl-1,5-dihydro-benzo[e][1,3]dithiepin-3-yl)-phenol | 2-(7,8-dimethyl-1,5-dihydro-2,4-benzodithiepin-3-yl)phenol | MLS000122801 | SMR000123419 | cid_596134
TypeSmall organic molecule
Emp. Form.C17H18OS2
Mol. Mass.302.454
SMILESCc1cc2CSC(SCc2cc1C)c1ccccc1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: