Reaction Details |
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Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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Ligand | BDBM67793 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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IC50 | 20700±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Mitochondrial import inner membrane translocase subunit TIM10 |
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Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 10303.50 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285809906 |
Residue: | 93 |
Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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BDBM67793 |
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n/a |
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Name | BDBM67793 |
Synonyms: | 2-(7,8-Dimethyl-1,5-dihydro-benzo[e][1,3]dithiepin-3-yl)-phenol | 2-(7,8-dimethyl-1,5-dihydro-2,4-benzodithiepin-3-yl)phenol | MLS000122801 | SMR000123419 | cid_596134 |
Type | Small organic molecule |
Emp. Form. | C17H18OS2 |
Mol. Mass. | 302.454 |
SMILES | Cc1cc2CSC(SCc2cc1C)c1ccccc1O |
Structure |
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