| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Ligand | BDBM65175 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
|---|
| IC50 | 8500±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 10303.50 |
|---|
| Organism: | Saccharomyces cerevisiae S288c |
|---|
| Description: | gi_285809906 |
|---|
| Residue: | 93 |
|---|
| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
|
|
|
|---|
| BDBM65175 |
|---|
| n/a |
|---|
| Name | BDBM65175 |
|---|
| Synonyms: | 1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluoromethyl)phenyl]thiourea | 1-[(2,4-dichlorophenyl)carbonylamino]-3-[3-(trifluoromethyl)phenyl]thiourea | 1-[[(2,4-dichlorophenyl)-oxomethyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea | MLS000588859 | SMR000212491 | cid_3729816 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H10Cl2F3N3OS |
|---|
| Mol. Mass. | 408.226 |
|---|
| SMILES | FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
