| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM57806 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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| IC50 | 47700±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM57806 |
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| n/a |
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| Name | BDBM57806 |
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| Synonyms: | 1-[1-(1-benzofuran-2-yl)ethylideneamino]-3-(3-methylphenyl)thiourea | 1-[1-(2-benzofuranyl)ethylideneamino]-3-(3-methylphenyl)thiourea | 1-[1-(benzofuran-2-yl)ethylideneamino]-3-(m-tolyl)thiourea | MLS000391554 | SMR000260589 | cid_4157752 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N3OS |
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| Mol. Mass. | 323.412 |
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| SMILES | CC(=NNC(=S)Nc1cccc(C)c1)c1cc2ccccc2o1 |w:2.2| |
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| Structure | 
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