| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
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| Ligand | BDBM46318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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| IC50 | 386±5 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ubiquitin-conjugating enzyme E2 N |
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| Name: | Ubiquitin-conjugating enzyme E2 N |
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| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17137.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101440 |
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| Residue: | 152 |
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| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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| BDBM46318 |
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| n/a |
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| Name | BDBM46318 |
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| Synonyms: | 2-amino-4-methyl-N'-(3,4,5-trimethoxybenzylidene)-1,3-thiazole-5-carbohydrazide | 2-amino-4-methyl-N-[(3,4,5-trimethoxybenzylidene)amino]thiazole-5-carboxamide | 2-amino-4-methyl-N-[(3,4,5-trimethoxyphenyl)methylideneamino]-1,3-thiazole-5-carboxamide | 2-amino-4-methyl-N-[(3,4,5-trimethoxyphenyl)methylideneamino]-5-thiazolecarboxamide | 2-azanyl-4-methyl-N-[(3,4,5-trimethoxyphenyl)methylideneamino]-1,3-thiazole-5-carboxamide | MLS000545601 | SMR000162971 | cid_1036441 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N4O4S |
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| Mol. Mass. | 350.393 |
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| SMILES | COc1cc(C=NNC(=O)c2sc(N)nc2C)cc(OC)c1OC |w:6.6| |
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| Structure | 
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