Reaction Details |
| Report a problem with these data |
Target | Ubiquitin-conjugating enzyme E2 N |
---|
Ligand | BDBM78669 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
---|
IC50 | 509±44 nM |
---|
Citation | PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Ubiquitin-conjugating enzyme E2 N |
---|
Name: | Ubiquitin-conjugating enzyme E2 N |
Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
Type: | PROTEIN |
Mol. Mass.: | 17137.61 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101440 |
Residue: | 152 |
Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
|
|
BDBM78669 |
---|
n/a |
---|
Name | BDBM78669 |
Synonyms: | 1-[(2-keto-5,7-dimethyl-indol-3-yl)amino]-3-(tetrahydrofurfuryl)thiourea | 1-[(5,7-dimethyl-2-oxidanylidene-indol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | 1-[(5,7-dimethyl-2-oxo-3-indolyl)amino]-3-(2-oxolanylmethyl)thiourea | 1-[(5,7-dimethyl-2-oxoindol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | MLS000417314 | SMR000242559 | cid_5992118 |
Type | Small organic molecule |
Emp. Form. | C16H20N4O2S |
Mol. Mass. | 332.421 |
SMILES | Cc1cc(C)c2=NC(=O)C(NNC(=S)NCC3CCCO3)=c2c1 |c:21,t:5| |
Structure |
|