Reaction Details |
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Target | Ubiquitin-conjugating enzyme E2 N |
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Ligand | BDBM52609 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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IC50 | 763±27 nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Ubiquitin-conjugating enzyme E2 N |
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Name: | Ubiquitin-conjugating enzyme E2 N |
Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
Type: | PROTEIN |
Mol. Mass.: | 17137.61 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101440 |
Residue: | 152 |
Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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BDBM52609 |
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n/a |
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Name | BDBM52609 |
Synonyms: | 1-(4-hydroxyphenyl)-3-[(2-ketoindol-3-yl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxidanylideneindol-3-yl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea | 1H-indole-2,3-dione 3-[N-(4-hydroxyphenyl)thiosemicarbazone] | MLS000673957 | SMR000298023 | cid_5345764 |
Type | Small organic molecule |
Emp. Form. | C15H12N4O2S |
Mol. Mass. | 312.346 |
SMILES | Oc1ccc(NC(=S)NNC2=c3ccccc3=NC2=O)cc1 |c:10,17| |
Structure |
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