| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
|---|
| Ligand | BDBM79117 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
|---|
| IC50 | 1465±28 nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Ubiquitin-conjugating enzyme E2 N |
|---|
| Name: | Ubiquitin-conjugating enzyme E2 N |
|---|
| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17137.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101440 |
|---|
| Residue: | 152 |
|---|
| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
|
|
|---|
| BDBM79117 |
|---|
| n/a |
|---|
| Name | BDBM79117 |
|---|
| Synonyms: | 2-[(2-keto-2-pyrrolidino-acetyl)amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxamide | 2-[[1,2-dioxo-2-(1-pyrrolidinyl)ethyl]amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxamide | 5,5-dimethyl-2-[(2-oxidanylidene-2-pyrrolidin-1-yl-ethanoyl)amino]-4,7-dihydrothieno[2,3-c]pyran-3-carboxamide | 5,5-dimethyl-2-[(2-oxo-2-pyrrolidin-1-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyran-3-carboxamide | MLS001158318 | SMR000652142 | cid_8034751 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21N3O4S |
|---|
| Mol. Mass. | 351.421 |
|---|
| SMILES | CC1(C)Cc2c(CO1)sc(NC(=O)C(=O)N1CCCC1)c2C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
