Ki Summary

Reaction Details

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Target

X-box-binding protein 1

Ligand

BDBM68005

Substrate/Competitor

n/a

Meas. Tech.

XBP1 DR counterscreen for CHOP

IC50

2440±n/a nM

Citation

PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

X-box-binding protein 1

Name:

X-box-binding protein 1

Synonyms:

TREB5 | XBP1 | XBP1_HUMAN | XBP2

Type:

Enzyme Catalytic Domain

Mol. Mass.:

28704.14

Organism:

Homo sapiens (Human)

Description:

gi_47678753

Residue:

261

Sequence:

MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK
RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR
EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL
SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP
YQPPFLCQWGRHQPSWKPLMN

BDBM68005

n/a

Name

BDBM68005

Synonyms:

1-[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxidanylidene-ethyl]sulfanyl-4-(2-methylpropyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 1-[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]sulfanyl-4-(2-methylpropyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 1-[[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]thio]-4-(2-methylpropyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 4-Isobutyl-1-[2-(2-methyl-2,3-dihydro-indol-1-yl)-2-oxo-ethylsulfanyl]-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 4-isobutyl-1-[[2-keto-2-(2-methylindolin-1-yl)ethyl]thio]-[1,2,4]triazolo[4,3-a]quinazolin-5-one | MLS000555318 | SMR000173630 | cid_3227896

Type

Small organic molecule

Emp. Form.

C24H25N5O2S

Mol. Mass.

447.553

SMILES

CC(C)Cn1c2nnc(SCC(=O)N3C(C)Cc4ccccc34)n2c2ccccc2c1=O

Structure